Laboratori di Biochimica e Biologia Molecolare

Settore ERC

Attività

I Laboratori di Biochimica e Biologia Molecolare del Campus dell'Università degli Studi di Parma sono sede di ricerca avanzata in aree della biologia funzionale e strutturale a livello molecolare e delle relative applicazioni biotecnologiche. 

Progetti

• In vivo-BRET drug discovery platform for the identification of protein-protein interaction inhibitors of biomedical interest
• A novel integrated and immunological strategy for the therapy of chronic hepatitis B
• Exploring the potential of Alu RNAs as novel epigenetic players and molecular biomarkers in cancer biology

Prodotti della ricerca

2018

Dieci, Giorgio, Ferrari, Roberto (2018)
The third (III) road to cell transformation.
https://air.unipr.it/handle/11381/2837868

Rota, Federica, Conti, Anastasia, Campo, Laura, Favero, Chiara, Cantone, Laura, Motta, Valeria, Polledri, Elisa, Mercadante, Rosa, Dieci, Giorgio, Bollati, Valentina, Fustinoni, Silvia (2018)
Epigenetic and transcriptional modifications in repetitive elements in petrol stationworkers exposed to benzene and MTBE.
https://air.unipr.it/handle/11381/2845267

Pouyanfard, Somayeh, Spagnoli, Gloria, Bulli, Lorenzo, Balz, Kathrin, Yang, Fan, Odenwald, Caroline, Seitz, Hanna, Mariz, Filipe C , Bolchi, Angelo, Ottonello, Simone, Müller, Martin (2018)
Minor capsid protein L2 polytope induces broad protection against oncogenic and mucosal human papillomaviruses.
https://air.unipr.it/handle/11381/2839736

Murat, Claude, Payen, Thibaut, Noel, Benjamin, Kuo, Alan, Morin, Emmanuelle, Chen, Juan, Kohler, Annegret, Krizsán, Krisztina, Balestrini, Raffaella, Da Silva, Corinne, Montanini, Barbara, Hainaut, Mathieu, Levati, Elisabetta, Barry, Kerrie W , Belfiori, Beatrice, Cichocki, Nicolas, Clum, Alicia, Dockter, Rhyan B , Fauchery, Laure, Guy, Julie, Iotti, Mirco, Le Tacon, François, Lindquist, Erika A , Lipzen, Anna, Malagnac, Fabienne, Mello, Antonietta, Molinier, Virginie, Miyauchi, Shingo, Poulain, Julie, Riccioni, Claudia, Rubini, Andrea, Sitrit, Yaron, Splivallo, Richard, Traeger, Stefanie, Wang, Mei, Žifčáková, Lucia, Wipf, Daniel, Zambonelli, Alessandra, Paolocci, Francesco, Nowrousian, Minou, Ottonello, Simone, Baldrian, Petr, Spatafora, Joseph W , Henrissat, Bernard, Nagy, Laszlo G , Aury, Jean-Marc, Wincker, Patrick, Grigoriev, Igor V , Bonfante, Paola, Martin, Francis M (2018)
Pezizomycetes genomes reveal the molecular basis of ectomycorrhizal truffle lifestyle.
https://air.unipr.it/handle/11381/2854923

2017

Carnevali, Davide, Dieci, Giorgio (2017)
Identification of RNA Polymerase III-Transcribed SINEs at Single-Locus Resolution from RNA Sequencing Data.
https://air.unipr.it/handle/11381/2822307

Carnevali, Davide, Conti, Anastasia, Pellegrini, Matteo, Dieci, Giorgio (2017)
Whole-genome expression analysis of mammalian-wide interspersed repeat elements in human cell lines.
https://air.unipr.it/handle/11381/2822303

Bosio, Maria Cristina, Fermi, Beatrice, Spagnoli, Gloria, Levati, Elisabetta, Rubbi, Ludmilla, Ferrari, Roberto, Pellegrini, Matteo, Dieci, Giorgio (2017)
Abf1 and other general regulatory factors control ribosome biogenesis gene expression in budding yeast.
https://air.unipr.it/handle/11381/2822305

Bosio, Maria Cristina, Fermi, Beatrice, Dieci, Giorgio (2017)
Transcriptional control of yeast ribosome biogenesis: a multifaceted role for General Regulatory Factors.
https://air.unipr.it/handle/11381/2822983

Fermi, Beatrice, Bosio, Maria Cristina, Dieci, Giorgio (2017)
Multiple roles of the general regulatory factor Abf1 in yeast ribosome biogenesis.
https://air.unipr.it/handle/11381/2822302

Daguerre, Y , Levati, E , Ruytinx, J , Tisserant, E , Morin, E , Kohler, A , Montanini, B , Ottonello, S , Brun, A , Veneault-Fourrey, C , Martin, F (2017)
Regulatory networks underlying mycorrhizal development delineated by genome-wide expression profiling and functional analysis of the transcription factor repertoire of the plant symbiotic fungus Laccaria bicolor.
https://air.unipr.it/handle/11381/2830172

Corbel, Caroline, Sartini, Sara, Levati, Elisabetta, Colas, Pierre, Maillet, Laurent, Couturier, Cyril, Montanini, Barbara, Bach, Stéphane (2017)
Screening for Protein-Protein Interaction Inhibitors Using a Bioluminescence Resonance Energy Transfer (BRET)-Based Assay in Yeast.
https://air.unipr.it/handle/11381/2828565

Fisicaro, Paola, Barili, Valeria, Montanini, Barbara, Acerbi, Greta, Ferracin, Manuela, Guerrieri, Francesca, Salerno, Debora, Boni, Carolina, Massari, Marco, Cavallo, M Cristina, Grossi, Glenda, Giuberti, Tiziana, Lampertico, Pietro, Missale, Gabriele, Levrero, Massimo, Ottonello, Simone, Ferrari, Carlo (2017)
Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B.
https://air.unipr.it/handle/11381/2822739

Matone, Alice, Derlindati, Eleonora, Marchetti, Luca, Spigoni, Valentina, Dei Cas, Alessandra, Montanini, Barbara, Ardigã², Diego, Zavaroni, Ivana, Priami, Corrado, Bonadonna, Riccardo (2017)
Identification of an early transcriptomic signature of insulin resistance and related diseases in lymphomonocytes of healthy subjects.
https://air.unipr.it/handle/11381/2832520

Mattarozzi, Monica, Manfredi, M, Montanini, Barbara, Gosetti, F, Sanangelantoni, Anna Maria, Marengo, E, Careri, Maria, Visioli, Giovanna (2017)
A metaproteomic approach dissecting major bacterial functions in the rhizosphere of plants living in serpentine soil.
https://air.unipr.it/handle/11381/2824518

Cavazzini, Davide, Grossi, Guido, Levati, Elisabetta, Vallese, Francesca, Montanini, Barbara, Bolchi, Angelo, Zanotti, Giuseppe, Ottonello, Simone (2017)
A family of archaea-like carboxylesterases preferentially expressed in the symbiotic phase of the mycorrhizal fungus Tuber melanosporum.
https://air.unipr.it/handle/11381/2830173

Gerace, Raffaele, Montanini, Barbara, Proietto, Marco, Levati, Elisabetta, De Luca, Cristina, Brenna, Andrea, Filetici, Patrizia, Kohler, Annegret, Ottonello, Simone, Ballario, Paola (2017)
Photoreceptors in the dark: A functional white collar-like complex and other putative light-sensing components encoded by the genome of the subterranean fungus Tuber melanosporum.
https://air.unipr.it/handle/11381/2822740

Spagnoli, Gloria, Pouyanfard, Somayeh, Cavazzini, Davide, Canali, Elena, Maggi, Stefano, Tommasino, Massimo, Bolchi, Angelo, Müller, Martin, Ottonello, Simone (2017)
Broadly neutralizing antiviral responses induced by a single-molecule HPV vaccine based on thermostable thioredoxin-L2 multiepitope nanoparticles.
https://air.unipr.it/handle/11381/2839738

Verna, Andrea Elizabeth, Franceschi, Valentina, Tebaldi, Giulia, Macchi, Francesca, Menozzi, Valentina, Pastori, Claudia, Lopalco, Lucia, Ottonello, Simone, Cavirani, Sandro, Donofrio, Gaetano (2017)
Induction of antihuman C-C chemokine receptor type 5 antibodies by a bovine herpesvirus type-4 based vector.
https://air.unipr.it/handle/11381/2839739

Spagnoli, Gloria, Bolchi, Angelo, Cavazzini, Davide, Pouyanfard, Somayeh, Müller, Martin, Ottonello, Simone (2017)
Secretory production of designed multipeptides displayed on a thermostable bacterial thioredoxin scaffold in Pichia pastoris.
https://air.unipr.it/handle/11381/2808762

2016

Conti, Anastasia, Rota, Federica, Ragni, Enrico, Favero, Chiara, Motta, Valeria, Lazzari, Lorenza, Bollati, Valentina, Fustinoni, Silvia, Dieci, Giorgio (2016)
Hydroquinone induces DNA hypomethylation-independent overexpression of retroelements in human leukemia and hematopoietic stem cells.
https://air.unipr.it/handle/11381/2808988

Fermi, Beatrice, Bosio, Maria Cristina, Dieci, Giorgio (2016)
Promoter architecture and transcriptional regulation of Abf1-dependent ribosomal protein genes in Saccharomyces cerevisiae.
https://air.unipr.it/handle/11381/2810040

Levati, Elisabetta, Sartini, Sara, Ottonello, Simone, Montanini, Barbara (2016)
Dry and wet approaches for genome-wide functional annotation of conventional and unconventional transcriptional activators.
https://air.unipr.it/handle/11381/2822738

Levati, Elisabetta, Sartini, Sara, Bolchi, Angelo, Ottonello, Simone, Montanini, Barbara (2016)
Moonlighting transcriptional activation function of a fungal sulfur metabolism enzyme.
https://air.unipr.it/handle/11381/2808705

Tebaldi, Giulia, Jacca, Sarah, Montanini, Barbara, Capra, Emanuele, Rosamilia, Alfonso, Sala, Arianna, Stella, Alessandra, Castiglioni, Bianca, Ottonello, Simone, Donofrio, Gaetano (2016)
Virus-Mediated Metalloproteinase 1 Induction Revealed by Transcriptome Profiling of Bovine Herpesvirus 4-Infected Bovine Endometrial Stromal Cells.
https://air.unipr.it/handle/11381/2808707

Jacca, Sarah, Rolih, Valeria, Quaglino, Elena, Franceschi, Valentina, Tebaldi, Giulia, Bolli Elisabetta, Rosamilia, Alfonso, Ottonello, Simone, Cavallo Federica, Donofrio, Gaetano (2016)
Bovine herpesvirus 4-based vector delivering a hybrid rat/human HER-2 oncoantigen efficiently protects mice from autochthonous Her-2+ mammary cancer.
https://air.unipr.it/handle/11381/2798544