PRESENT RESEARCH ACTIVITY
Research activity in the Stress Physiology Lab is mainly focused on the biological substrates of depression/anxiety and autonomic/cardiovascular dysfunction comorbidity. This topic is approached via preclinical research on animal models of depression (based on adverse social conditions) and anxiety (based on lines selectively bred). Proendocannabinoid pharmacological treatment (FAAH inhibition) is tested to verify its pevention/reversal potential over behavioral and physiological symptoms of anxiety/depression as well as over autonomic/cardiovascular dysfunction. Part of the lab research activity is also devoted to the evaluation of a number of chronic stress parameters in various human populations. Ongoing collaborations: (a) Dept of Behavioral Physiology - Univ. Groningen (NL; profs. S. De Boer and P. Meerlo), (b) School of Biomedical Sciences & Pharmacy - Univ. Newcastle (AUS; prof. E. Nalivaiko), (c) Dept. of Neurobiology and Animal Physiology - Univ. Regensburg (GER; prof. I. Neumann), (d) Dept. of Psychology - NWU Chicago (USA; prof. A. Grippo), (e) Dept. of Pharmacy - Univ. of Parma (IT; profs. M. Mor and S. Rivara), (f) Dept. of Medicine & Surgery - Univ. of Parma (IT; prof. P.F. Ferrari)
RESEARCH KEY WORDS
Stress, chronic social stress, biological stress markers, anxiety, depression, coping styles, social behavior, hypothalamic-pituitary-adrenocortical axis, sympathetic-adrenomedullary system, autonomic nervous system, heart rate variability, cardiovascular physiology and pathophysiology, arrhythmias, rodent model of empathy
ARTICLES in INTERNATIONAL PEER-REVIEWED JOURNALS 2017-2018
Carnevali, Luca, Koenig, Julian, Sgoifo, Andrea, Ottaviani, Cristina (2018)
Autonomic and Brain Morphological Predictors of Stress Resilience.
Carnevali, Luca, Statello, ROSARIO IGNAZIO, Sgoifo, Andrea (2018)
The Utility of Rodent Models of Stress for Disentangling Individual Vulnerability to Depression and Cardiovascular Comorbidity.
Statello, Rosario, Carnevali, Luca, Alinovi, Davide, Pisani, Francesco, Sgoifo, Andrea (2018)
Heart rate variability in neonatal patients with seizures.
Statello, R, Carnevali, L, Paterlini, S, Gioiosa, L, Bertocchi, I, Oberto, A, Eva, C, Palanza, P, Sgoifo, A (2017)
Reduced NPY Y1 receptor hippocampal expression and signs of decreased vagal modulation of heart rate in mice.
Carnevali, Luca, Montano, Nicola, Statello, Rosario, Sgoifo, Andrea (2017)
Rodent models of depression-cardiovascular comorbidity: Bridging the known to the new.
Carnevali, L , Rivara, S , Nalivaiko, E, Thayer, J F, Vacondio, F, Mor, M , Sgoifo, A (2017)
Pharmacological inhibition of FAAH activity in rodents: A promising pharmacological approach for psychological-cardiac comorbidity?
Villada, Carolina, Espin, Laura, Hidalgo, Vanesa, Rubagotti, Sara, Sgoifo, Andrea, Salvador, Alicia (2017)
The influence of coping strategies and behavior on the physiological response to social stress in women: The role of age and menstrual cycle phase.
Sgoifo, A , Montano, N, Esler, M , Vaccarino, V (2017)
Stress, behavior and the heart.
Walker, F R , Pfingst, K , Carnevali, Luca, Sgoifo, Andrea, Nalivaiko, E (2017)
In the search for integrative biomarker of resilience to psychological stress.
Carnevali, Luca, Montano, Nicola, Statello, ROSARIO IGNAZIO, Coude', , Gino, Vacondio, Federica, Rivara, Silvia, Ferrari, Pier Francesco, Sgoifo, Andrea (2017)
Social stress contagion in rats: Behavioural, autonomic and neuroendocrine correlates.
Fornari, Mauro, Carnevali, Luca, Sgoifo, Andrea (2017)
Single osteopathic manipulative therapy session dampens acute autonomic and neuroendocrine responses to mental stress in healthy male participants.
Rossi, S , Buccarello, A , Ershler, P R , Lux, R L , Callegari, S , Corradi, D , Carnevali, L , Sgoifo, A , Miragoli, M , Musso, E , Macchi, E (2017)
Effect of anisotropy on ventricular vulnerability to unidirectional block and reentry by single premature stimulation during normal sinus rhythm in rat heart.
Ferrario, Chiara, Statello, ROSARIO IGNAZIO, Carnevali, L, Mancabelli, Leonardo, Milani, Christian, Mangifesta, Marta, Duranti, Sabrina, Lugli, Gabriele Andrea, Jimenez, B, Lodge, S, Viappiani, Anna Luisa, Alessandri, Giulia, Dall', Asta, Margherita, Del Rio, D, Sgoifo, Andrea, Van, Sinderen, Ventura, Marco, Turroni, Francesca (2017)
How to feed the mammalian gut microbiota: bacterial and metabolic modulation by dietary fibers.
Referente progetti Erasmus per il CdS in Biologia e Applicazioni Biomediche