Crystal Engineering

Componenti

  1. Bacchi Prof.ssa Alessia (Coordinatore)
  2. Pelagatti Prof. Paolo (Coordinatore)
  3. Mazzeo Prof. Paolo Pio (Coordinatore)
  4. Prencipe Michele (Dottorando)
  5. Giovanardi Dott. Dario (Dottorando)
  6. Cicconi Giuditta (Studente)
  7. Casali Alessandro (Dottorando)
  8. Piombo Beatrice (Studente)
  9. Cagossi Giorgio (Dottorando)
  10. Abodunrin Olabise Temitope (Membro)
  11. Napolitano Marta (Borsista)
  12. Martina Orlandini (Membro)

Attività

Settore ERC

PE4_3 - Molecular architecture and Structure
PE5_1 - Structural properties of materials
PE5_2 - Solid state materials
PE5_8 - Intelligent materials - self assembled materials
PE5_10 - Coordination chemistry

The group research interests are focused on crystal engineering of polymorphs, solvates, co-crystals, and of responsive organic/inorganic materials. Within this broad theme we developed crystalline molecular and polymeric (MOF) materials capable to reversibly capture and release volatile guestsin a solid/gas and solid/liquid exchange, and proposed structural models to map the process of molecular recognition between the crystalline receptor and the volatile substrate. Recently we focused on the design and control of crystal forms of molecular compounds, and on the stabilization inside crystalline structures (MOF and cocrystals) of liquid and volatile compounds related to human health, environment and nutrition.

Prodotti della ricerca

Delledonne, Andrea, Orlandini, Martina, Mazzeo, Paolo P, Sissa, Cristina, Bacchi, Alessia, Terenziani, Francesca, Pelagatti, Paolo (2022)
Bis-isonicotinoyl linkers containing polyaromatic scaffolds: synthesis, structure and spectroscopic properties.
https://air.unipr.it/handle/11381/2910392
Baraldi, L , Fornasari, L , Bassanetti, I , Amadei, F , Bacchi, A , Marchio', , L (2022)
Salification Controls the In-Vitro Release of Theophylline.
https://air.unipr.it/handle/11381/2916268
Dadi, A , Mazzeo, P P , Bacchi, A , Loukil, M (2022)
Synthesis, crystal structure, structural phase transition and dielectric properties of new organic-inorganic hybrid compound: (C6H5CH2N(C2H5)3)CdCl3.
https://air.unipr.it/handle/11381/2920249
Bianchi, F , Fornari, F , Riboni, N , Spadini, C , Cabassi, C S , Iannarelli, M , Carraro, C , Mazzeo, P P , Bacchi, A , Orlandini, S , Furlanetto, S , Careri, M (2021)
Development of novel cocrystal-based active food packaging by a quality by design approach.
https://air.unipr.it/handle/11381/2886694
Balestri, D , Mazzeo, P P , Perrone, R , Fornari, F , Bianchi, F , Careri, M , Bacchi, A , Pelagatti, P (2021)
Deciphering the Supramolecular Organization of Multiple Guests Inside a Microporous MOF to Understand their Release Profile.
https://air.unipr.it/handle/11381/2892805
Bacchi, A , Mazzeo, P P (2021)
Cocrystallization as a tool to stabilize liquid active ingredients.
https://air.unipr.it/handle/11381/2898533.1
Lampronti, G I , Michalchuk, A A L , Mazzeo, P P , Belenguer, A M , Sanders, J K M , Bacchi, A , Emmerling, F (2021)
Changing the game of time resolved X-ray diffraction on the mechanochemistry playground by downsizing.
https://air.unipr.it/handle/11381/2902365
Stevanovic, N , Mazzeo, P P , Bacchi, A , Matic, I Z , Dordic Crnogorac, M , Stanojkovic, T , Vujcic, M , Novakovic, I , Radanovic, D , Sumar-Ristovic, M , Sladic, D , Cobeljic, B , Andelkovic, K (2021)
Synthesis, characterization, antimicrobial and cytotoxic activity and DNA-binding properties of d-metal complexes with hydrazones of Girard’s T and P reagents.
https://air.unipr.it/handle/11381/2898535
Sala, A , Hoossen, Z , Bacchi, A , Caira, M R (2021)
Two crystal forms of a hydrated 2:1 b-cyclodextrin× fluconazole complex: Single crystal x-ray structures, dehydration profiles, and conditions for their individual isolation.
https://air.unipr.it/handle/11381/2899946
Mazzeo, Paolo Pio, Balestri, Davide, Bacchi, Alessia, Pelagatti, Paolo (2021)
Stabilization of liquid active guests via nanoconfinement into a flexible microporous Metal-Organic Framework.
https://air.unipr.it/handle/11381/2912964
Priola, E , Giordana, A , Mazzeo, P P , Mahmoudi, G , Gomila, R M , Zubkov, F I , Pokazeev, K M , Valchuk, K S , Bacchi, A , Zangrando, E , Frontera, A (2021)
On the nature of recurrent Au⋯π motifs in tris(2,2′-bipyridine)M(ii) (M = Fe, Co and Ni) dicyanoaurate(i) salts: X-ray analysis and theoretical rationalization.
https://air.unipr.it/handle/11381/2911095
Mazzeo, P P , Pioli, M , Montisci, F , Bacchi, A , Pelagatti, P (2021)
Mechanochemical Preparation of Dipyridyl-Naphthalenediimide Cocrystals: Relative Role of Halogen-Bond and π-πInteractions.
https://air.unipr.it/handle/11381/2898537
Mazzeo, P P , Canossa, S , Carraro, C , Pelagatti, P , Bacchi, A (2020)
Systematic coformer contribution to cocrystal stabilization: Energy and packing trends.
https://air.unipr.it/handle/11381/2885036
Pioli, M , Loffi, C , Mazzeo, P P , Bacchi, A , Pelagatti, P (2020)
Synthesis, spectroscopic and structural characterization and solution stability of ruthenium sandwich complexes containing 1,8-naphthalimide ligands.
https://air.unipr.it/handle/11381/2886392
Mazzeo, Paolo P , Carraro, Claudia, Arns, Anthea, Pelagatti, Paolo, Bacchi, Alessia (2020)
Diversity through similarity: a world of polymorphs, solid solutions, cocrystals in a vial of 4,4'-diazopyridine.
https://air.unipr.it/handle/11381/2869911
Biscarini, P , Bilotti, I , Ferranti, F , Bacchi, A , Pelizzi, G , Mikolajczyk, M , Drabowicz, J (2020)
The chiral 1:2 adduct (S)S(S)C(-)589-ethyl 2-phenylbutyl sulphide-mercury (II) chloride:(-)589[(S)S(S)C-Et(2-PhBu)S.(HgCl2)2]. Stereoselective synthesis, asymmetric oxidation, crystal and molecular structure and circular dichroism spectra.
https://air.unipr.it/handle/11381/2881854
Cruz-Cabeza, Aurora J , Wright, Sarah E , Bacchi, Alessia (2020)
On the entropy cost of making solvates.
https://air.unipr.it/handle/11381/2879273
Pancrazzi, F , Sarti, N , Mazzeo, P P , Bacchi, A , Carfagna, C , Mancuso, R , Gabriele, B , Costa, M , Stirling, A , Della Ca', , N (2020)
Site-Selective Double and Tetracyclization Routes to Fused Polyheterocyclic Structures by Pd-Catalyzed Carbonylation Reactions.
https://air.unipr.it/handle/11381/2873751
Bianchi, F , Pankajakshan, A , Fornari, F , Mandal, S , Pelagatti, P , Bacchi, A , Mazzeo, P P , Careri, M (2020)
A zinc mixed-ligand microporous metal-organic framework as solid-phase microextraction coating for priority polycyclic aromatic hydrocarbons from water samples.
https://air.unipr.it/handle/11381/2874281
Mazzeo, Paolo P , Bacchi, Alessia, Pelagatti, Paolo (2020)
Crystal engineering guidelines for ruthenium based wheel-and-axle compounds.
https://air.unipr.it/handle/11381/2882708
Ben Abdallah, Mohamed Amine, Bacchi, Alessia, Parisini, Antonella, Canossa, Stefano, Bergamonti, Laura, Balestri, Davide, Kamoun, Slaheddine (2020)
Crystal structure, vibrational, electrical, optical and DFT study of C2H10N2(IO3)2.HIO3.
https://air.unipr.it/handle/11381/2875508
Canossa, Stefano, Fornasari, Luca, Demitri, Nicola, Mattarozzi, Monica, Choquesillo-Lazarte, Duane, Pelagatti, Paolo, Bacchi, Alessia (2019)
MOF transmetalation beyond cation substitution: Defective distortion of IRMOF-9 in the spotlight.
https://air.unipr.it/handle/11381/2857851
Balestri, D , Scilabra, P , Carraro, Claudia, Delledonne, A , Bacchi, A , Mazzeo, P P , Carlucci, L , Pelagatti, P (2019)
Structural, thermal and topological characterization of coordination networks containing flexible aminocarboxylate ligands with a central biphenylene scaffold.
https://air.unipr.it/handle/11381/2866307
Ben Abdallah, Mohamed Amine, Bacchi, Alessia, Parisini, Antonella, Canossa, Stefano, Mazzeo, Paolo Pio, Bergamonti, Laura, Kamoun, Slaheddine (2019)
X-ray, optical, vibrational, electrical, and DFT study of the polymorphic structure of ethylenediammonium bis iodate α-C2H10N2(IO3)2 and β-C2H10N2(IO3)2.
https://air.unipr.it/handle/11381/2858118
Puentes, Roberto, Torres, Julia, Faccio, Ricardo, Bacchi, Alessia, Kremer, Carlos (2019)
Lanthanide coordination polymers based on flexible ligands derived from iminodiacetic acid.
https://air.unipr.it/handle/11381/2866359
Mahmoudi, G , Seth, S K , Zubkov, F I , Lopez-Torres, E , Bacchi, A , Stilinovic, V , Frontera, A (2019)
Supramolecular assemblies in Pb(II) complexes with hydrazido-based ligands.
https://air.unipr.it/handle/11381/2866362
Balestri, D , Mazzeo, P P , Carraro, C , Demitri, N , Pelagatti, P , Bacchi, A (2019)
Stepwise Evolution of Molecular Nanoaggregates Inside the Pores of a Highly Flexible Metal–Organic Framework.
https://air.unipr.it/handle/11381/2866310
Mazzeo, Paolo Pio, Carraro, Claudia, Andrea, Monica, Capucci, Davide, Pelagatti, Paolo, Bianchi, Federica, Agazzi, Silvia, Careri, Maria, Aida, Raio, Marina, Carta, Felicia, Menicucci, Mattia, Belli, Marco, Michelozzi, Bacchi, Alessia (2019)
Designing a palette of Cocrystals based on Essential Oil constituents for agricultural applications.
https://air.unipr.it/handle/11381/2863639
Ben Abdallah, Mohamed Amine, Bacchi, Alessia, Parisini, Antonella, Mazzeo, Paolo Pio, Terenziani, Francesca, Marchiò, Luciano, Kamoun, Slaheddine (2019)
Structure, vibrational, electrical and optical study of [C2H10N2] (IO3)2·4HIO3.
https://air.unipr.it/handle/11381/2853806
Casnati, Alessandra, Perrone, Antonio, Mazzeo, Paolo P , Bacchi, Alessia, Mancuso, Raffaella, Gabriele, Bartolo, Maggi, Raimondo, Maestri, Giovanni, Motti, Elena, Stirling, András, Della Ca', , Nicola (2019)
Synthesis of Imidazolidin-2-ones and Imidazol-2-ones via Base-Catalyzed Intramolecular Hydroamidation of Propargylic Ureas under Ambient Conditions.
https://air.unipr.it/handle/11381/2857813
Balestri, Davide, Bassanetti, Irene, Canossa, Stefano, Gazzurelli, Cristina, Bacchi, Alessia, Silvia, Bracco, Angiolina, Comotti, Pelagatti, Paolo (2018)
Changing the Dress to a MOF through Fluorination and Transmetalation. Structural and Gas-Sorption Effects.
https://air.unipr.it/handle/11381/2850963
Balestri, Davide, Bacchi, Alessia, Scilabra, Patrick, Pelagatti, Paolo (2018)
Extension of the Pd-catalyzed CN bond forming reaction to the synthesis of large polydentate ligands containing NH functions.
https://air.unipr.it/handle/11381/2835620
Canossa, Stefano, Pelagatti, Paolo, Bacchi, Alessia (2018)
Drinking and Breathing: Solvent Coordination-driven Plasticity of IRMOF-9.
https://air.unipr.it/handle/11381/2858182
Bacchi, Alessia (2018)
The Use of Databases in the Study of Intermolecular Interactions.
https://air.unipr.it/handle/11381/2848821
Balestri, Davide, Costa, Davide, Bacchi, Alessia, Lucia, Carlucci, Pelagatti, Paolo (2018)
Linker dependent dimensionality in Zn(II)-coordination polymers containing a flexible bis-pyridyl-bis-amide ligand.
https://air.unipr.it/handle/11381/2850962

Bacchi, Alessia (2018)
The Use of Databases in the Study of Intermolecular Interactions.
https://air.unipr.it/handle/11381/2848821

Balestri, Davide, Bassanetti, Irene, Canossa, Stefano, Gazzurelli, Cristina, Bacchi, Alessia, Bracco, Silvia, Comotti, Angiolina, Pelagatti, Paolo (2018)
Changing the Dress to a MOF through Fluorination and Transmetalation. Structural and Gas-Sorption Effects.
https://air.unipr.it/handle/11381/2850963

Bacchi, Alessia (2018)
Intermolecular Interactions in Crystals.
https://air.unipr.it/handle/11381/2851756

Canossa, Stefano, Bacchi, Alessia, Graiff, Claudia, Pelagatti, Paolo, Predieri, Giovanni, Ienco, Andrea, Manca, Gabriele, Mealli, Carlo (2017)
Hierarchy of Supramolecular Arrangements and Building Blocks: Inverted Paradigm of Crystal Engineering in the Unprecedented Metal Coordination of Methylene Blue.
https://air.unipr.it/handle/11381/2822879

Paolo, Pagano, Pelagatti, Paolo, Bacchi, Alessia, Michele R , Chierotti, Susan A , Bourne, Gift, Mehlana (2017)
SORPTION PROPERTIES TOWARDS ENVIRONMENTALLY IMPORTANT VOCs of HALF-SANDWICH Ru(II) COMPLEXES CONTAINING PERYLENE-BIS-IMIDE LIGANDS.
https://air.unipr.it/handle/11381/2827570

Capucci, Davide, Balestri, Davide, Mazzeo, PAOLO PIO, Pelagatti, Paolo, Rubini, K , Bacchi, Alessia (2017)
Liquid Nicotine Tamed in Solid Forms by Cocrystallization.
https://air.unipr.it/handle/11381/2830678

Mahmoudi, Ghodrat, Gurbanov, Atash V , Rodríguez-Hermida, Sabina, Carballo, Rosa, Amini, Mojtaba, Bacchi, Alessia, Mitoraj, Mariusz P , Sagan, Filip, Kukulka, Mercedes, Safin, Damir A (2017)
Ligand-Driven Coordination Sphere-Induced Engineering of Hybride Materials Constructed from PbCl2 and Bis-Pyridyl Organic Linkers for Single-Component Light-Emitting Phosphors.
https://air.unipr.it/handle/11381/2848811

Alessia Bacchi, *, Davide Capucci, †, Marco Giannetto, †, Monica Mattarozzi, †, Paolo Pelagatti, †, Nair Rodriguez-Hornedo, †, Katia Rubini, ‡, Andrea, Sala (2016)
Turning Liquid Propofol into Solid (without Freezing It): Thermodynamic Characterization of Pharmaceutical Cocrystals Built with a Liquid Drug.
https://air.unipr.it/handle/11381/2817274

Bacchi, Alessia (2016)
Crystallography - A very short introduction.
https://air.unipr.it/handle/11381/2817889

Puentes, Roberto, Torres, Julia, Kremer, Carlos, Cano, Joan, Lloret, Francesc, Capucci, Davide, Bacchi, Alessia (2016)
Mononuclear and polynuclear complexes ligated by an iminodiacetic acid derivative: synthesis, structure, solution studies and magnetic properties.
https://air.unipr.it/handle/11381/2806070

Micheli, Fabrizio, Bacchi, Alessia, Braggio, Simone, Castelletti, Laura, Cavallini, Palmina, Cavanni, Paolo, Cremonesi, Susanna, Dal Cin, Michele, Feriani, Aldo, Gehanne, Sylvie, Kajbaf, Mahmud, Marchio', , Luciano, Nola, Selena, Oliosi, Beatrice, Pellacani, Annalisa, Perdonà, Elisabetta, Sava, Anna, Semeraro, Teresa, Tarsi, Luca, Tomelleri, Silvia, Wong, Andrea, Visentini, Filippo, Zonzini, Laura, Heidbreder, Christian (2016)
1,2,4-Triazolyl 5-Azaspiro[2.4]heptanes: Lead Identification and Early Lead Optimization of a New Series of Potent and Selective Dopamine D3 Receptor Antagonists.
https://air.unipr.it/handle/11381/2817890

Bacchi, Alessia, Pelagatti, Paolo (2016)
Organometallic chemistry meets crystal engineering to give responsive crystalline materials.
https://air.unipr.it/handle/11381/2806069

Chierotti, Michele R , Roberto, Gobetto, Carlo, Nervi, Bacchi, Alessia, Pelagatti, Paolo, Valentina, Colombo, Angelo, Sironi (2014)
Probing Hydrogen Bond Networks in Half-Sandwich Ru(II) Building Blocks by a Combined1H DQ CRAMPS Solid-State NMR, XRPD, and DFT Approach.
https://air.unipr.it/handle/11381/2670065

A Bacchi, A Brillante, D Crocco, M R Chierotti, R G Della Valle, A Girlando, M Masino, P Pelagatti, E Venuti (2014)
Exploration of the polymorph landscape for 1,1,4,4-tetraphenyl-1,3-butadiene.
https://air.unipr.it/handle/11381/2761702

Bacchi, Alessia, Cantoni, Giulia, Crocco, Domenico, Granelli, M , Pagano, P , Pelagatti, Paolo (2014)
Hydrogen-bond networks in polymorphs and solvates of metallorganic complexes containing ruthenium and aminoamide ligands.
https://air.unipr.it/handle/11381/2670066

Giuseppe M Lombardo, Antonio Rescifina, Ugo Chiacchio, Alessia Bacchi, Francesco Punzo (2014)
A top–down approach to crystal engineering of a racemic Δ2-isoxazoline.
https://air.unipr.it/handle/11381/2761703

Bacchi, Alessia, Cantoni, Giulia, Pelagatti, Paolo (2013)
Polymorphs and co-crystal with half-sandwich Ru(ii) dimers [(η6-arene)RuX2]2.
https://air.unipr.it/handle/11381/2682095

Bacchi, Alessia, G , Cantoni, Mezzadri, Francesco, Pelagatti, Paolo (2012)
From Local Control to Collective Response: Fabrication ofResponsive Organometallic Crystalline Materials by Careful Design ofFunctionalities and Tailoring of the Intermolecular Interactions.
https://air.unipr.it/handle/11381/2450836

Balestri, Davide, Bassanetti, Irene, Canossa, Stefano, Gazzurelli, Cristina, Bacchi, Alessia, Bracco, Silvia, Comotti, Angiolina, Pelagatti, Paolo (2018)
Changing the Dress to a MOF through Fluorination and Transmetalation. Structural and Gas-Sorption Effects.
https://air.unipr.it/handle/11381/2850963

Capucci, Davide, Balestri, Davide, Mazzeo, PAOLO PIO, Pelagatti, Paolo, Rubini, K , Bacchi, Alessia (2017)
Liquid Nicotine Tamed in Solid Forms by Cocrystallization.
https://air.unipr.it/handle/11381/2830678

Alessia Bacchi, *, Davide Capucci, †, Marco Giannetto, †, Monica Mattarozzi, †, Paolo Pelagatti, †, Nair Rodriguez-Hornedo, †, Katia Rubini, ‡, Andrea, Sala (2016)
Turning Liquid Propofol into Solid (without Freezing It): Thermodynamic Characterization of Pharmaceutical Cocrystals Built with a Liquid Drug.
https://air.unipr.it/handle/11381/2817274

Bacchi, Alessia, Pelagatti, Paolo (2016)
Organometallic chemistry meets crystal engineering to give responsive crystalline materials.
https://air.unipr.it/handle/11381/2806069